Transactions 2006 Through Monday, June 26th
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| Team Name | Replaced | Picked Up |
| Camel Jockeys | Released - Daniel Cabrera | Jon Lester |
| Rooster Rage | Released - Shawn Green | Ryan Freel |
| Non - Smokers | Released - Miguel Olivo | Michael Barrett |
| Asian Pranksters | Released - Conor Jackson | Activated - Albert Pujols |
| Winged Buffalo | Released - Reggie Sanders | Mike Cameron |
| Rooster Rage | Released - Damian Miller | John Buck |
| Non - Smokers | Released - Jeff Francis | Activated - Jason Isringhausen |
| Non - Smokers | Reserved - Trevor Hoffman (3rd time) | Nate Robertson |
| Sultans of Swat | Reserved - Zach Duke | Jorge Sosa |
| Winged Buffalo | Reserved - Brian Schneider | Mike Napoli |
| Iron Men | Released - Jose Castillo | Activated - Derrek Lee |
| The Bigg Doggs | DL - Mark Mulder | Activated - A.J. Burnett |
| Camel Jockeys | Released - Horacio Ramirez | No Open Spot |
| A.C.L. | Released - Elizardo Ramirez | Activated - John Patterson |
| A.C.L. | Released - Orlando Hernandez | Zach Miner |
| Non - Smokers | Reserved - Tim Hudson | Jamie Shields |
| Rooster Rage | Reserved - Matt Cain | Jason Jennings |
| Rooster Rage | Reserved - Barry Bonds | Craig Wilson |
| Sultans of Swat | Reserved - Jonny Gomes | Eric Byrnes |
| Sultans of Swat | Released - Michael Cuddyer | No Open Spot |
| Winged Buffalo | Released - Jarrod Washburn | No Open Spot |
| A.C.L. | Released - Xavier Nady | No Open Spot |