Transactions 2006 Through Monday, April 17th
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| Team Name | Replaced | Picked Up |
| Harpooners | Released - Danny Graves | J.J. Putz |
| Non - Smokers | DL - Sean Casey | Brad Hawpe |
| Camel Jockeys | Released - Juan Encarnacion | Craig Wilson |
| Make 7up Yours | DL - Aubrey Huff | Phil Nevin |
| Iron Men | Released - Dan Miceli | Scot Shields |
| The Bigg Doggs | DL - Brandon Backe | Activated - A.J. Burnett |
| Rooster Rage | DL - Ian Kinsler | Shannon Stewart |
| Camel Jockeys | Released - Kyle Davies | John Thomson |
| Iron Men | Released - Cory Sullivan | Ryan Church |
| Camel Jockeys | Released - Dave Roberts | Kevin Youkilis |
| Camel Jockeys | Reserved - Edgar Renteria | Luis Castillo |
| Iron Men | Reserved - Shawn Chacon | Activated - Kelvim Escobar |
| Harpooners | DL - Chipper Jones | Ty Wiggington |
| A.C.L. | DL - Ryan Doumit | Humberto Cota |
| A.C.L. | DL - Dmitri Young | Xavier Nady |
| A.C.L. | Released - Aaron Heilman | No Open Spot |
| A.C.L. | Released - Orlando Hernandez | Scott Baker |
| Camel Jockeys | Reserved - Gustavo Chacin | Daniel Cabrera |
| Non - Smokers | DL - Ken Griffey | Casey Blake |
| Non - Smokers | Reserve - Ryan Zimmerman | Conor Jackson |