Transactions 2006 Through Monday, September 18th
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| Team Name | Replaced | Picked Up |
| The Bigg Doggs | Taxi - Francisco Liriano | Activated - Jason Marquis |
| Sultans of Swat | Taxi - Scot Shields | Activated - Carlos Zambrano |
| Sultans of Swat | Released - Jonathan Broxton | No Open Spot |
| Winged Buffalo | Taxi - Manny Ramirez | Activated - Brian Giles |
| Winged Buffalo | Taxi - Mike Sweeney | Activated - Adrian Beltre |