Transactions 2008 Through Monday, September 22nd
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| Team Name | Replaced | Picked Up |
| Reserve Moves | ||
| Sultans of Swat | Taxi - Mike Pelfrey | Activated - Jesse Litsch |
| The Bigg Doggs | Released - Michael Bourn | Activated - J.D. Drew |
| Winged Buffalo | Taxi - Willy Taveras | Activated - Shin-Soo Choo |