Transactions 2009 Through Monday, September 28th
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| Team Name | Replaced | Picked Up |
| BALCO Bombers | Released - Jonny Gomes | Activated - Dexter Fowler |
| BALCO Bombers | Released - Mike MacDougal | Activated - Jake Peavy |
| Iron Men | Released - Randy Johnson | No Open Spot |
| Non - Smokers | Released - John Maine | No Open Spot |
| Winged Buffalo | Released - Taylor Teagarden | Activated - Ramon Hernandez |
| I Like Big Bunts | Released - Aaron Cook | No Open Spot |
| Reserve Moves | ||
| The Bigg Doggs | Taxi - Marco Scutaro | Activated - Asdrubal Cabrera |
| The Bigg Doggs | Taxi - Clayton Richard | Activated - Aaron Laffey |
| Reversal of Fortune | Taxi - Ryan Theriot | Activated - Yunel Escobar |
| Reversal of Fortune | Taxi - Macier Izturis | Activated - Michael Young |
| I Like Big Bunts | Taxi - Rich Harden | Activated - Daisuke Matsuzaka |
| I Like Big Bunts | Taxi - Cody Ross | Activated - Kosuke Fukudome |
| A.C.L. | Taxi - Billy Wagner | Activated - Anibal Sanchez |
| Iron Men | Taxi - Max Scherzer | Activated - Michael Wuertz |
| Iron Men | Taxi - Franklin Morales | Activated - Huston Street |
| Iron Men | Taxi - Willie Bloomquist | Activated - Jermaine Dye |