| Pick | Owner | Pos | Player | Rnd | Year | ||
| Round 1 | |||||||
| 1 | Guilmet | SP | Jacob deGrom | 1 | 2021 | ||
| 2 | Scott | OF | Christian Yelich | 1 | 2021 | ||
| 3 | Mike | OF, 1B | Cody Bellinger | 1 | 2021 | ||
| 4 | Chris | SP | Trevor Bauer | 1 | 2021 | ||
| 5 | Rick | SP | Aaron Nola | 1 | 2021 | ||
| 6 | Jeff | OF | Aaron Judge | 1 | 2021 | ||
| Round 2 | |||||||
| 7 | Eric | 2B, OF | Whit Merrifield | 2 | 2021 | ||
| 8 | Rick | 3B | Anthony Rendon | 2 | 2021 | ||
| 9 | Russ | SP | Corbin Burnes | 2 | 2021 | ||
| 10 | Chris | OF | Starling Marte | 2 | 2021 | ||
| 11 | Craig | OF | Marcell Ozuna | 2 | 2021 | ||
| 12 | Mike | OF | Kyle Lewis | 2 | 2021 | ||
| 13 | Scott | SS | Javier Baez | 2 | 2021 | ||
| 14 | Guilmet | SS | Carlos Correa | 2 | 2021 | ||
| Round 3 | |||||||
| 15 | Chris | OF | Michael Conforto | 3 | 2021 | ||
| 16 | Rick | SP | Jose Berrios | 3 | 2021 | ||
| 17 | Scott | 1B | Paul Goldschmidt | 3 | 2021 | ||
| 18 | Russ | SP | Ian Anderson | 3 | 2021 | ||
| 19 | Craig | SP | Pablo Lopez | 3 | 2021 | ||
| 20 | Guilmet | SP | Stephen Strasburg | 3 | 2021 | ||
| 21 | Jeff | OF | Eddie Rosario | 3 | 2021 | ||
| Round 4 | |||||||
| 22 | Jeff | 1B, 2B | Mike Moustakas | 4 | 2021 | ||
| 23 | Guilmet | 2B | Jose Altuve | 4 | 2021 | ||
| 24 | Phil | DH | Giancarlo Stanton | 4 | 2021 | ||
| 25 | Russ | 1B | Anthony Rizzo | 4 | 2021 | ||
| 26 | Mike | OF | Randy Arozarena | 4 | 2021 | ||
| 27 | Eric | OF | Teoscar Hernandez | 4 | 2021 | ||
| 28 | Scott | OF | Nick Castellanos | 4 | 2021 | ||
| 29 | Rick | DH | J.D. Martinez | 4 | 2021 | ||
| 30 | Chris | SP | Zack Greinke | 4 | 2021 | ||
| Round 5 | |||||||
| 31 | Jeff | SP | Corey Kluber | 5 | 2021 | ||
| 32 | Guilmet | SP | Dylan Bundy | 5 | 2021 | ||
| 33 | Mike | SP | Kevin Gausman | 5 | 2021 | ||
| 34 | Phil | SP | Lance McCullers Jr. | 5 | 2021 | ||
| 35 | Craig | DH | Nelson Cruz | 5 | 2021 | ||
| 36 | Chris | 3B | Kris Bryant | 5 | 2021 | ||
| 37 | Eric | SP | Kyle Hendricks | 5 | 2021 | ||
| 38 | Scott | C | Mitch Garver | 5 | 2021 | ||
| Round 6 | |||||||
| 39 | Scott | SP | Shohei Ohtani | 6 | 2021 | ||
| 40 | Jason | RP | Ryan Pressly | 6 | 2021 | ||
| 41 | Chris | OF | Trent Grisham | 6 | 2021 | ||
| 42 | Craig | SP | Jose Urquidy | 6 | 2021 | ||
| 43 | Phil | OF | Max Kepler | 6 | 2021 | ||
| 44 | Rick | 2B, 3B, OF | Jeff McNeil | 6 | 2021 | ||
| 45 | Mike | RP | Kenley Jansen | 6 | 2021 | ||
| 46 | Guilmet | RP | Edwin Diaz | 6 | 2021 | ||
| 47 | Scott | SP | Noah Syndergaard | 6 | 2021 | ||
| 48 | Jeff | OF | Joey Gallo | 6 | 2021 | ||
| Round 7 | |||||||
| 49 | Guilmet | C | Willson Contreras | 7 | 2021 | ||
| 50 | Chris | RP | Raisel Iglesias | 7 | 2021 | ||
| 51 | Rick | RP | James Karinchak | 7 | 2021 | ||
| 52 | Phil | 3B | Josh Donaldson | 7 | 2021 | ||
| 53 | Farrelly | SP | Joe Musgrove | 7 | 2021 | ||
| 54 | Eric | SP | Sixto Sanchez | 7 | 2021 | ||
| 55 | Mike | SP | Tyler Mahle | 7 | 2021 | ||
| 56 | Jeff | SP | Marcus Stroman | 7 | 2021 | ||
| 57 | Craig | SP | Trevor Rogers | 7 | 2021 | ||
| 58 | Jason | SP | Aaron Civale | 7 | 2021 | ||
| 59 | Russ | 2B, OF | Dylan Moore | 7 | 2021 | ||
| Round 8 | |||||||
| 60 | Russ | C | Travis d'Arnaud | 8 | 2021 | ||
| 61 | Jason | SP | Zach Eflin | 8 | 2021 | ||
| 62 | Craig | SS | Didi Gregorius | 8 | 2021 | ||
| 63 | Jeff | SP | Jameson Taillon | 8 | 2021 | ||
| 64 | Eric | OF | Byron Buxton | 8 | 2021 | ||
| 65 | Scott | 1B | C.J. Cron | 8 | 2021 | ||
| 66 | Farrelly | OF | Ramon Laureano | 8 | 2021 | ||
| 67 | Phil | 1B | Rhys Hoskins | 8 | 2021 | ||
| 68 | Chris | SP | Carlos Carrasco | 8 | 2021 | ||
| 69 | Guilmet | RP | Taylor Rogers | 8 | 2021 | ||
| Round 9 | |||||||
| 70 | Phil | RP | Brad Hand | 9 | 2021 | ||
| 71 | Jason | SP | Andrew Heaney | 9 | 2021 | ||
| 72 | Mike | 2B, SS, 3B | Andres Gimenez | 9 | 2021 | ||
| 73 | Russ | 1B, 3B | Alec Bohm | 9 | 2021 | ||
| 74 | Rick | OF | Wil Myers | 9 | 2021 | ||
| 75 | Eric | 3B | Ke'Bryan Hayes | 9 | 2021 | ||
| 76 | Chris | OF, 1B | Dominic Smith | 9 | 2021 | ||
| 77 | Jeff | C | Gary Sanchez | 9 | 2021 | ||
| 78 | Craig | OF | Leody Taveras | 9 | 2021 | ||
| 79 | Scott | OF | Tommy Pham | 9 | 2021 | ||
| Round 10 | |||||||
| 80 | Scott | RP | Trevor Rosenthal | 10 | 2021 | ||
| 81 | Craig | RP | Craig Kimbrel | 10 | 2021 | ||
| 82 | Chris | C | Yasmani Grandal | 10 | 2021 | ||
| 83 | Eric | 1B, OF | Ryan Mountcastle | 10 | 2021 | ||
| 84 | Rick | OF | Mike Yastrzemski | 10 | 2021 | ||
| 85 | Farrelly | SP | Elieser Hernandez | 10 | 2021 | ||
| 86 | Mike | RP | Drew Pomeranz | 10 | 2021 | ||
| 87 | Phil | 1B, 2B, SS | Jake Cronenworth | 10 | 2021 | ||
| Round 11 | |||||||
| 88 | Mike | OF | Kyle Schwarber | 11 | 2021 | ||
| 89 | Chris | SP | Chris Sale | 11 | 2021 | ||
| 90 | Phil | SP | Tarik Skubal | 11 | 2021 | ||
| 91 | Eric | SP | Frankie Montas | 11 | 2021 | ||
| 92 | Craig | SS | Josh Rojas | 11 | 2021 | ||
| 93 | Farrelly | SP | James Paxton | 11 | 2021 | ||
| 94 | Jason | SP | Cristian Javier | 11 | 2021 | ||
| Round 12 | |||||||
| 95 | Jason | SP | Drew Smyly | 12 | 2021 | ||
| 96 | Farrelly | 2B | Jean Segura | 12 | 2021 | ||
| 97 | Craig | RP | Will Smith | 12 | 2021 | ||
| 98 | Mike | C | Christian Vazquez | 12 | 2021 | ||
| 99 | Rick | RP | Rafael Montero | 12 | 2021 | ||
| Round 13 | |||||||
| 100 | Craig | SP | David Price | 13 | 2021 | ||
| 101 | Farrelly | OF | Clint Frazier | 13 | 2021 | ||
| Round 14 | |||||||
| 102 | Mike | SP | Chris Bassitt | 14 | 2021 | ||
| 103 | Chris | OF | Dylan Carlson | 14 | 2021 | ||
| 104 | Farrelly | SP | Casey Mize | 14 | 2021 | ||
| 105 | Phil | OF | Cristian Pache | 14 | 2021 | ||
| 106 | Craig | 3B | Gio Urshela | 14 | 2021 | ||
| 107 | Jeff | 1B | Andrew Vaughn | 14 | 2021 | ||
| 108 | Jason | OF | Mitch Haniger | 14 | 2021 | ||
| 109 | Eric | SP | Dustin May | 14 | 2021 | ||
| Round 15 | |||||||
| 110 | Phil | C | Sean Murphy | 15 | 2021 | ||
| 111 | Craig | C | James McCann | 15 | 2021 | ||
| 112 | Rick | SP | Marco Gonzales | 15 | 2021 | ||
| 113 | Jason | 2B, SS, 3B, OF | Tommy Edman | 15 | 2021 | ||
| 114 | Scott | RP | Jordan Romano | 15 | 2021 | ||
| 115 | Eric | SP | Triston McKenzie | 15 | 2021 | ||
| 116 | Chris | OF | Anthony Santander | 15 | 2021 | ||
| 117 | Russ | OF | Jesse Winker | 15 | 2021 | ||
| 118 | Guilmet | OF | Michael Brantley | 15 | 2021 | ||
| Round 16 | |||||||
| 119 | Guilmet | OF | Randal Grichuk | 16 | 2021 | ||
| 120 | Russ | OF | Adam Duvall | 16 | 2021 | ||
| 121 | Eric | 2B, OF | Nick Solak | 16 | 2021 | ||
| 122 | Scott | SP | Nathan Eovaldi | 16 | 2021 | ||
| 123 | Mike | C | Carson Kelly | 16 | 2021 | ||
| 124 | Jeff | SP | Framber Valdez | 16 | 2021 | ||
| 125 | Jason | 2B | Gavin Lux | 16 | 2021 | ||
| 126 | Rick | OF | Andrew Benintendi | 16 | 2021 | ||
| 127 | Craig | OF | Raimel Tapia | 16 | 2021 | ||
| 128 | Farrelly | RP | Matt Barnes | 16 | 2021 | ||
| Round 17 | |||||||
| 129 | Eric | RP | Amir Garrett | 17 | 2021 | ||
| 130 | Phil | SP | Justus Sheffield | 17 | 2021 | ||
| 131 | Jason | RP | Jordan Hicks | 17 | 2021 | ||
| 132 | Rick | 2B | Jorge Polanco | 17 | 2021 | ||
| 133 | Jeff | 3B | Austin Riley | 17 | 2021 | ||
| 134 | Russ | 1B | Miguel Sano | 17 | 2021 | ||
| 135 | Farrelly | 2B | Nick Madrigal | 17 | 2021 | ||
| 136 | Guilmet | C | Buster Posey | 17 | 2021 | ||
| 137 | Craig | SP | German Marquez | 17 | 2021 | ||
| Round 18 | |||||||
| 138 | Farrelly | C | Austin Nola | 18 | 2021 | ||
| 139 | Russ | OF | Nick Senzel | 18 | 2021 | ||
| 140 | Jeff | SP | Mike Clevinger | 18 | 2021 | ||
| 141 | Jason | 1B | Christian Walker | 18 | 2021 | ||
| Round 19 | |||||||
| 142 | Scott | OF | Joc Pederson | 19 | 2021 | ||
| 143 | Farrelly | OF | Lorenzo Cain | 19 | 2021 | ||
| 144 | Guilmet | OF | Justin Upton | 19 | 2021 | ||
| 145 | Jason | C | Jorge Alfaro | 19 | 2021 | ||
| 146 | Rick | RP | Alex Colome | 19 | 2021 | ||
| 147 | Russ | 2B | Kolten Wong | 19 | 2021 | ||
| Round 20 | |||||||
| 148 | Phil | SP | Luis Severino | 20 | 2021 | ||
| 149 | Russ | C | Yan Gomes | 20 | 2021 | ||
| 150 | Farrelly | OF | AJ Pollock | 20 | 2021 | ||
| 151 | Scott | C | Wilson Ramos | 20 | 2021 | ||
| 152 | Craig | OF | Andrew McCutchen | 20 | 2021 | ||
| 153 | Mike | RP | Hector Neris | 20 | 2021 | ||
| Round 21 | |||||||
| 154 | Jason | OF | Manuel Margot | 21 | 2021 | ||
| 155 | Guilmet | 3B | Justin Turner | 21 | 2021 | ||
| 156 | Russ | SP | Nate Pearson | 21 | 2021 | ||
| 157 | Chris | 3B | Kyle Seager | 21 | 2021 | ||
| 158 | Craig | SP | Domingo German | 21 | 2021 | ||
| 159 | Farrelly | C | Danny Jansen | 21 | 2021 | ||
| 160 | Jeff | OF | Hunter Renfroe | 21 | 2021 | ||
| 161 | Scott | SP | Robbie Ray | 21 | 2021 | ||
| 162 | Phil | 3B, OF | J.D. Davis | 21 | 2021 | ||
| 163 | Eric | C | Francisco Mejia | 21 | 2021 | ||
| Round 22 | |||||||
| 164 | Eric | 1B, OF | Hunter Dozier | 22 | 2021 | ||
| 165 | Rick | C | Omar Narvaez | 22 | 2021 | ||
| 166 | Phil | SP | Brad Keller | 22 | 2021 | ||
| 167 | Jeff | SS | Willy Adames | 22 | 2021 | ||
| 168 | Farrelly | OF | Franchy Cordero | 22 | 2021 | ||
| 169 | Mike | SP | Jordan Montgomery | 22 | 2021 | ||
| 170 | Craig | C | Yadier Molina | 22 | 2021 | ||
| 171 | Chris | 1B | Carlos Santana | 22 | 2021 | ||
| 172 | Russ | RP | Daniel Bard | 22 | 2021 | ||
| 173 | Guilmet | 1B | Brandon Belt | 22 | 2021 | ||
| 174 | Jason | SP | Yusei Kikuchi | 22 | 2021 | ||
| Round 23 | |||||||
| 175 | Craig | SP | Adam Wainwright | 23 | 2021 | ||
| 176 | Jeff | OF | Bryan Reynolds | 23 | 2021 | ||
| 177 | Farrelly | SP | Matthew Boyd | 23 | 2021 | ||
| 178 | Guilmet | SP | Michael Pineda | 23 | 2021 | ||
| 179 | Scott | 2B, SS | Jazz Chisholm | 23 | 2021 | ||
| 180 | Chris | RP | Richard Rodriguez | 23 | 2021 | ||
| 181 | Rick | SP | Brady Singer | 23 | 2021 | ||
| 182 | Mike | OF | Kole Calhoun | 23 | 2021 | ||
| 183 | Jason | C | Tom Murphy | 23 | 2021 | ||
| 184 | Eric | C | Alejandro Kirk | 23 | 2021 | ||
| 185 | Phil | C | Jose Trevino | 23 | 2021 | ||
| Minors - Round 1 | |||||||
| 1 | Jeff | 3B | Spencer Torkelson | 18X | |||
| 2 | Eric | OF | Jarred Kelenic | 18X | |||
| 3 | Scott | OF | Julio Rodriguez | 18X | |||
| 4 | Rick | SS | Bobby Witt Jr. | 18X | |||
| 5 | Jason | OF | Alex Kirilloff | 18X | |||
| 6 | Phil | SP | MacKenzie Gore | 18X | |||
| 7 | Russ | C | Adley Rutschman | 18X | |||
| 8 | Chris | SS | CJ Abrams | 18X | |||
| 9 | Farrelly | RP | Luis Patino | 18X | |||
| 10 | Craig | SP | Matt Manning | 18X | K | ||
| 11 | Mike | SP | Forrest Whitley | 18X | |||
| 12 | Guilmet | SS | Austin Martin | 18X | |||
| Minors - Round 2 | |||||||
| 13 | Guilmet | SS | Marco Luciano | 19X | |||
| 14 | Mike | SS | Royce Lewis | 19X | |||
| 15 | Craig | OF | Jo Adell | 19X | |||
| 16 | Farrelly | OF | JJ Bleday | 19X | |||
| 17 | Chris | SS | Wander Franco | 19X | K | ||
| 18 | Russ | OF | Jarren Duran | 19X | |||
| 19 | Phil | 3B | Nolan Gorman | 19X | |||
| 20 | Jason | SS | Jeter Downs | 19X | |||
| 21 | Rick | 3B | Triston Casas | 19X | |||
| 22 | Scott | OF | Jasson Dominguez | 19X | |||
| 23 | Eric | OF | Riley Greene | 19X | |||
| 24 | Jeff | SP | Brailyn Marquez | 19X | |||
| Minors - Round 3 | |||||||
| 25 | Jeff | SP | Grayson Rodriguez | 20X | |||
| 26 | Eric | SP | Max Meyer | 20X | |||
| 27 | Scott | SP | Logan Gilbert | 20X | |||
| 28 | Rick | OF | Trevor Larnach | 20X | |||
| 29 | Jason | OF | Brennen Davis | 20X | |||
| 30 | Phil | SS | Oneil Cruz | 20X | |||
| 31 | Russ | 3B | Josh Jung | 20X | |||
| 32 | Chris | OF | Corbin Carroll | 20X | |||
| 33 | Farrelly | SP | Deivi Garcia | 20X | |||
| 34 | Craig | OF | Kristian Robinson | 20X | K | ||
| 35 | Mike | SP | Asa Lacy | 20X | |||
| 36 | Guilmet | C | Joey Bart | 20X | |||